Friday, March 7, 2014

Epistasis: A limitation for twin studies?

Several faculty members at ITW2014 mentioned epistasis as a potential limitation of class twin studies. Epistasis describes the potential possibility that the effect of one gene depends on the effect of one or more other genes. The question is, how problematic is epistasis for twin researchers?

Professor David Evans explained that epistatsis is usually now a serious problem (whewww!) because it happens very rarely and therefore it's highly unlikely that the particular phenotype you are studying suffers from epistasis.

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